No, once build it stays there until you do something to reset it ( changing game version, changing the graphics preset, game being updated or launching in safe mode )

So it d3d crashed when i tried to to a new game. Once i change graphics to medium, i will have to recache shaders right?

引用自 Shamyeh：

So it d3d crashed when i tried to to a new game. Once i change graphics to medium, i will have to recache shaders right?

check the d3d sticky post in discussions, should only be 1 setting to change