- Immaculate Conception Stacking will reduce by 2 the number of hearts for it to trigger both its effects(familiar and heart spawn)

- Curse Of The Tower Stacking will spawn more bomb trolls when getting hit

- Cambion Conception Stacking will reduce the number of hits for each threshold to trigger by 2

- The Mind Stacking will also show the Ultra Secret Room
- Little Baggy Stacking will convert all pills into its Horse version(pills can still have negative effects!!)

- Trisagion Stacking will reduce shot speed by 0.05

- Brittle Bones Stacking will further reduce tear delay when losing a bone heart

- Whore Of Babylon Stacking: stats will now stack when item is active

- Ghost Pepper and Bird's Eye will increase fire size by 50% and damage by 25% per extra copy
- Eye Drops will further reduce tear delay by 0.5
- Money = Power will increase damage per coin by 100%

- Mr Mega stacking will increase bomb damage by 25%

- Fanny Pack stacking will make that each copy of the item has a 50% chance of spawning a random pickup