I'm using Spriter Pro to animate characters for a school project. It doesn't take long to learn, and you can create some really nice animations with it. Automatically exports frames into .png images, a single spritesheet, or even an animated .gif! Even has a mode to turn high-res images into pixel art. And it does make some decent pixel art out of them, they don't turn all blurry and such. Looks nice and crisp.

I'm using Spriter Pro to animate characters for a school project. It doesn't take long to learn, and you can create some really nice animations with it. Automatically exports frames into .png images, a single spritesheet, or even an animated .gif! Even has a mode to turn high-res images into pixel art. And it does make some decent pixel art out of them, they don't turn all blurry and such. Looks nice and crisp.