Good News Everyone!

Planet Express was founded by Professor Hubert J. Farnsworth as method of funding his research in 2961. At that time, Zoidberg was already an employee, and a delivery crew had recently been hired, consisting of Lando Tucker, Candy, and Lifter, although on their first delivery, the three were swallowed by a Four-dimensional space whale. (Zoidberg panicked and took the escape pod), which began the long line of delivery crews. The first employee of the year was then 13-year-old Amy Wong. Amy has supposedly not worked with the company from the beginning, as she does not seem to know any of the multiple previous crews before the current. While little is known about Planet Express' early history, we know that Hermes Conrad has been with the company for as early as 2993.
Besides regular staff, such as Hermes Conrad, bureaucrat, and interns, such as Amy Wong, the company's most important positions are the starship crew, who pilot the Planet Express ship during deliveries, and essentially support the business itself. Even though it is not officially in their job descriptions, the rest of the staff often tag along on the ship during missions.
Planet Express has had a history of security issues, several prior crews to Turanga Leela, Philip J. Fry and Bender Bending Rodríguez have apparently been lost or killed during difficult missions, which Farnsworth relentlessly sent them out on. The current crew can be assumed to be the most successful crew so far, in terms of survival, although the professor still asserted that they are not as good as his previous crew.
At least two former crews are known to exist, one lead by Captain Musky and another which was killed by either Space wasps or Space bees. Alternatively, these may have been two crews entirely. The first crew was swallowed by a four-dimensional space whale, but survived until 3010, with Lifter and Candy not aging, while Lando Tucker nearly sucked dry due to the whale's feeding. According to this crew, they too were not as good as the crew prior to them. Farnsworth may simply tell all his crews this as a form of motivation. Farnsworth himself doesn't think highly of the chances of his crew surviving, at one point he is evidently looking for a replacement crew before they even leave.