I think you might have to elaborate more on what difference you are referring too? Are you asking what the difference between the DE and classic version of this mod is, other than that they are for different versions of the game?

I think it was pretty obvious that he's asking what is the difference between "More Monster Spawns" and "Monster Madness"

This

Ah, ok my apologies, I am a dumbo. The difference is this one(More Monster Spawns) adds more monsters to old fights, for instance the croc fight has several extra crocs in it. The other one(Monster Madness) adds new fights to the map, for instance there is a herd of zombies on top of where you first find a shovel before you reach fort joy. Both mods are compatable with each other.