Unfortunately this didn't work for me. It seems that the game runs a check to see what version of PhysX is used and it seems to re-install the old version that comes with the steam release. Tried running in almost all OS compatibilities but nothing.

Thanks! It worked for me!

@Dahn

Info from Steam Guide - https://psteamcommunity.yuanyoumao.com/sharedfiles/filedetails/?id=1110994164
Info from PC Gaming Wiki- https://www.pcgamingwiki.com/wiki/Space_Siege#No_Mouse_Cursor

Another idea - maybe load DGVoodoo (a wrapper for older DirectX games, as some have issues on newer Windows OS's) into Space Siege folder & configure that all up. See if that does the trick.

All Dungeon Siege games also have the mouse cursor issues, so...Space Siege probably has the same issue and is probably also on the Siege Engine.

Thank you very much!
It loads again which is great!

Now, I have to try to work out why my cursor disappears and why I cannot do anything in the menu screen ;-)

Thanks worked a treat.

ty very much

Thanks man!