Tower Wizard has a very satisfying and complex series of resource mechanics that allow you to increasing ascend/scale the tower to completion. The cost of the resources increases exponentially, placing an effective ceiling on the available resources and forcing players to optimize use of the in-game mechanics; or use gained Prestige points to unlock a selection of Blessings (buffs) to allow further advancement.

Mechanics are listed in the order they are or can be encountered:

• Orb - 1st Ascension - Spirit summons Cloudling which produces Magic to make more Spirits
  
• Study - 2nd Ascension - Spirit summons Library Tome which produces Knowledge to buy ingame buffs and buildings
  
• Forestry - 3rd Ascension - Spirit summons Druid which produces Wood to buy Totem buffs.
  
• Prestige - 4th Ascension - Points are gain thru lifetime Magic and Damage used to allocate to Blessings, at cost of resetting tower build.
  
• Building / Spirit Housing - Allows for building of Academy, Dragon Nest, and Embassy from Knowledge, and provides 4 free Houses which each tower ascension which can augment Magic, Knowledge, or Wood gain
  
• Academy - Spirit summons Sage, Research augments Magic, Forestry, Dragon, and Alchemy
  
• Dragon Nest - Spirit summons Keeper, growing dragon gives Abilities which augment Knowledge, Acedemy, Magic, Alchemy Lab, or Fireball
  
• Embassy - Spriit summons Diplomats, Trade gains Trade Agreements to Nations which provide fixed buffs; Diplomats are refunded after Trade Agreements reached with all Nations
  
• Alchemy Lab - Spirit summons Alchemist, creates Magic Gold, which allows creation of Relics which provide buffs to Magic, Knowledge, and Dragon
  
• Sorcery - Spirit summons Shaman, Ifrit, Gorgon, and Zephyr
  
• Runecraft - Spirit summons Runesmith, Runes can be used for various buffs
  
• Temple - ...
  
• ...

The later mechanics are way more powerful and synergistic than the earlier mechanics. The exception is the Prestige system, whose Blessings are also locked in tiers, provide the scaling to advance to the later parts of game.

In particular, while resources scale exponentially in cost, the buffs from the mechanics and the prestige system are generally speaking linear multiplicative. Furthermore, without the Prestige Blessing system, a run can expect to gather no more than about 100 Spirits, thereby effectively limiting forward progress. Therefore, the only effective path to completing the game is: to gain prestige Points to raise the exponential cap limit on Spirits, thereby enabling the user to advance further into the game's later mechanics to win.

• Hold-click on a focused mechanic will increase progress, works on most mechanics, including Sorcery. There's pretty much always some mechanic one can hold-click to help.
  
• Things can be built in increments of 10 by holding Shift while clicking.
  
• The shortcut bar at the top of the screen will highlight when the Orb is ready to ascend.
  
• Use the Resources bar on the left of the screen to see if you have things to spend
  
• Dont overspend Spirits in early mechanics that would be better spent on the more powerful later mechanics.
  
• Prestige Points are cumulatively earned (and earned even before unlocking the mechanic itself) and can only be earned two ways, so focus in early game on Magic. Later, apply one of the below damage strategies based on prestige progress.
  
• Blessing of Population can be really useful when slogging through the Embassy run.

Generally speaking, the Blessings that directly impact the later game mechanics are way more powerful than the earlier ones. Also, the last tier of blessings are downrated due to the high likelihood of completing the game before they are unlocked.

• A-tier Blessings: Research, Totems, Dragon, Alchemy, and Runecraft.
  
• B-tier Blessings: Dragon Wisdom, Fire, 60, Doubling, Multitasking, Crafting Totem, Specialization
  
• C-tier Blessings: Supervision, Balance, Population, Debt, Forest Keeper, Compounding
  
• D-tier Blessings: Magic, Knowledge, Forest, Sage Totem, Effects
  
• F-tier Blessings: Curses, Gorgon, Diplomacy, Few

• Early: Zephyr + Dragon and/or another unit in a support role;
  
• Mid: Dragon Fireball + Sage; alternatively Curse is ok
  
• Late: Dragon Fireball + Ifrit Molten + Blessing of Fire

The below walkthrough requires only prestiging after collecting enough Points for: 5, 10-11, and 21+, and can be done quickly

Objective is to ascend to unlock Prestige mechanic, while gaining as much Magic as possible to unlock 5 Prestige Points. 5 Prestige Points is needed to unlock the 2nd tier of Blessings for the next run.

• Initially build about 2-3 Wood Totems, then focus on Magic Totems.
  
• 12-16 Druids and Tomes, rest on Cloudlings

Blessings: Research+2, Totems (suggest Supervision and Magic)
Objective is to use Academy, Dragon, and at very end Alchemist to unlock 5-6 Prestige Points with Magic gain. The next 5 Prestige Points is needed for all the necessary 3rd tier of Blessings for the next run.

• 4-6 Wood Totems, then split between Knowledge and Magic, biasing Knowledge early.
  
• Suggest no more than 30 Cloudlings, Tomes, and Druids, save Spirits for Academy, Dragon, and Alchemy
  
• Use Dragon as a support role, and spread allocate Ability points as they come in
  
• Take advantage of the free Spirit Houses to rebalance your need for Magic or Knowledge
  
• Skip building the Embassy with this run
  
• When Alchemy is unlocked, focus only on Mana Stones to boost Magic for Prestige Points.

Blessings: Research+2, Totems, Alchemy+2, Dragon+2, Dragon Wisdom, Supervision (suggest Balance/Population, Magic/Knowledge)
Objective is to unlock 21+ total Prestige Points for the 3rd last Prestige Run. This run is long and will need to advance through the Embassy path without the related Blessings. There is also a huge need for Knowledge as the Embassy and later Combat and Rune Mastery buffs are extremely expensive but important.

• 6-8 Wood Totems, then split between Knowledge and Magic, largely biasing Knowledge over Magic.
  
• No more than 30 Cloudlings, Tomes, and Druids, saving Spirits for Embassy and later mechanics.
  
• Dragon continues as a support role, but is triple effective due to blessings. Can save some dragon ability for Fireball while you are doing the Embassy run; or just rely on Sorcery for damage.
  
• Slog thru the Embassy run as fast as possible using hold-click and dumping in Spirits
  
• Suggest initial Spirit House allocations as Book Houses for Knowledge
  
• Try not to overallocate spirits to destroy the Cloud Wall. Use 60 Zephyrs + some other supplement like Shamans and Dragon.
  
• Unlock only the runes for Zephyr lightning, Infinity, and maybe Alchemy Boost. Spend rest of points gaining Inifinity Runes to boost damage.
  
• Hold-click on the Sorcery to boost the damage and the Zephyr scaling

Blessings: Research+2, Totems, Alchemy+2, Dragon+2, Dragon Wisdom, Supervision, Fire+2, 60+2, Doubling, Multitasking, Runecraft+2, Crafting Totem+2, Specialization (suggest Balance/Population)
Importantly you've autounlocked the Blessing of Destruction augment.

• Suggest mostly building all Spirit Houses as Book Houses for Knowledge
  
• 12 Wood Totems initially, then into Crafting, then split between Wood and Crafting
  
• No more than 60 Cloudlings, Tomes, and Druids, saving Spirits for Embassy and later mechanics.
  
• Alchemy just builds Ouroboros to augment Fireball
  
• Dragon goes into Fireball mode, do not allocate any ability points until Dragon gains Fireball, then dump them in. Dragon Fireball + Ouroboros is more than capable of destroying the Cloud Wall with some help from Combat Magic buffs.
  
• Embassy run, head directly for Chronara then run thru the clockwise path as fast as possible, with liberal use of hold-click.
  
• After embassy, raise Sage, Dragon, Alchemy, Runesmith allocation to 60 to gain blessing buff.
  
• After getting all Runes, get 60 Ifrits first, then 60 of everything else.
  
• On Infinity Wall, focus first on gaining levels for Forest Keeper and building Wood Totems.