First Contact
In the bathroom on the floor
[Kill spiders using the revolver without reloading]
No need to restart
Energy Drinks is recommended if you cannot hit them, but not needed
Aim, and shoot, don't panic spam shoot, it will make them run even faster


First Contact - Halloween mode - Paranormal Contact
In the bathroom on the floor
[Kill spiders using he vaccum]
No need to restart
No need Energy Drinks
Suck up 100% of items into the Vacuum before starting
Start Challenge, then aim at the spiders with the Vacuum and hit them until they die


Close Encounters
In the panic room on the shelf
[Get shotgun kills]
Restart only if you are out of ammo
Energy Drinks is recommended if you cannot hit them, but not needed
Aim, and shoot, don't panic spam shoot, it will make them run even faster


Close Encounters - Halloween mode - Last Rites
By the exit door on the floor
[Kill Queens without killing spiderlings]
Use Energy Drinks for accuracy, need about 4 to 5 in total
Avoid using anything with fire / area of impact, the Clipboard is quite suitable
Walk around the corridor and the room, they might spawn there instead


Domestic Duty
In the garage on the shelf
[Kill spiders with fire]
Restart only if you are out of ammo
No need Energy Drinks
Use Hairspray, no need to hold, just light taps will suffice
If you have other fire weapons you can also use them


Domestic Duty - Halloween mode - Sticky Situation
In the garage on the floor where the car was
[get Frying pan kills without getting webbed]
No need to restart, I do suggest clearing all the existing spiders first
No need Energy Drinks
Throw Cheese Puffs in a circle around the Challenge Orbs, around 10 will do
Start challenge and run in a circle around the Challenge Orb killing the distracted spiders


Down the Spider Hole
In the basement on the floor
Need to solve the code first, you will then get a new weapon, the Shoe
[Kill spiders with the Shoe]
The Shoe upgrades with each kill, making it stronger and increasing the splash damage radius
Recommend playing other levels and getting kills with the shoe before returning
Alternatively restart this level, get a lot of easy kills from the holes, and then doing the challenge
With an upgraded Shoe you do not need Energy Drinks, just spam hit the floor by the exit


Major Inconvenience
On the counter by spawn
[Quickly kill spiders without using explosives]
Restart is recommended since more spiders are more potential kills
Energy Drinks are recommended since there is very little time
Fire takes too long to kill, but can help identify location of moving spiders easier
The Pan / Vacuum / Shoe are pretty good for this


Garden of Evil
On the ledge of the Shrine
[Kill spiders with Shurikens]
The Shuriken has a very annoying hit-box, especially when you're crouched
Remember to pick up a Shuriken immediately after throwing it
Energy Drinks are recommended, feels almost impossible to play without it
Restart is not necessary since the spiders under the rocks are even harder to hit
Spiders are easiest to hit then they are running towards / away from you in a straight line vertically, not horizontally


Barnstormer
In the Barn on a table
[Kill spiders using the assault rifle without reloading]
No need to restart
Energy Drinks is highly recommended
Aim, and shoot, don't panic spam shoot


Paper trail
In the office with the radioactive spiders on a table
[Kill 10 spiders using 10 different methods]
Restart for more spiders and max ammo, restart if you fail the Challenge or look around for ammo first
Energy Drinks is highly recommended, time is quite short
Press Q or Y and look at all your weapons and keybinds, make sure they are as accessible as possible, time is paused when you are looking at inventory, change out the weapons you got a kill with for easier identification, also make sure you have 10 different types of weapons, if not you need to find them from previous levels
Kill a spider with the weapon in slot 3, then swap to next weapon in slot 4 with your mouse wheel, keep track of which weapon you are using before chugging a new Energy Drink.
Suck up some items into your vacuum if you are planning to use it
Highly recommend upgrading your tracker so you can easily identify where spiders are


Contingency Omega
Automatically starts when you insert all 3 chips into the console
[Kill 30 spiders]
Restart level after completion
Get ready with Energy Drinks in hand
Burn everything, keep drinking Energy Drinks
At the end of the countdown use Explosives / Pan to quickly finish the last ones off


Consequences
Outside on a table, press the Red button instead of the Boombox
[Face the Consequences]
Instead of spiders, you now have to kill a bunch of cockroaches
No need to Restart
Energy Drinks highly recommended
Any method works really, I simply used fire and a pan, chugging Energy Drinks on the way


Congratulations, you now have access to the final room in Consequences.
Cargo Pants will grant you infinite ammo for all weapons.
Arachno-Scope will allow your tracker to see spiders through walls.
Good luck, and have fun! :)