Total Achievements: (24)
100% completion time: ~2-6 hours (Varies).
Difficulty modes:

• Normal
  
• Hard (Recommended)

New Game+: No
Missables: Yes
Mode: Single-player

Achievement Types:
1) Story Related: (6)
2) Kill: (6)
3) Collectables: (1)
4) Roguelike: (11)

Average completion story (w/o deaths) based on skills also: 2.5 hours
Endemic mode (Floor 9): ~2 hours

Endoparasitic is a linear survival horror game featuring a unique gameplay (QWOP but easy mouse controlled gameplay).

My hours also add up during the early days.

All achievements are earned through single playthrough and they are easy to not miss but alternatively since Endemic mode is unlockable from the start like Hard you can do that too but we will do Story > Endemic, be sure to select hard mode too. I included the Endemic mode and also the upgrades it can offer (WIP)

The Bag Master achievement (found on the last two achievements of this guide) are upgrade inventory slots you can find and you may miss some so be sure to check everywhere but if you miss them then no doubt reload your backup save because this game does have unlimited saves which I prepared in case achievement patch arrives.

As for hardcore, be careful when getting hit, no saves occur most of the time and enemies like the rats have increased behaviour reaction so I suggest playing the offensive style. Hardcore mode change the way you play:
- Save points are disabled.
- Less ammo and syringes.
- More damage to yourself by the enemies.
- The AI behavior has been altered by rats with their speed and reaction increased as opposed to easily dealing with them on normal mode.

2022/11/14:
During the 14th of November, 2022, the game has hardcore mode so basically depending how many times you died you can still get the cheevos easily because while it took ~3 hours or less the game remain the same but of course at least there is a different changes such as no save points excluding the next level autosave and of course the AI behavior such as the rat crawling faster than the normal mode which used to be easy to shoot and react to.

2023/05/18:
New roguelike mode with achievements hehe more

!! Warning: Spoilers ahead !!

1) Level: Revolver, Shotgun, Flare
2) Bags: 4/6
3) Achievements: 6/24
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Story should not take long to complete, still I will go over areas that have the achievements and collectable as well on bags.

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Field Medic
Cauterize your wounds
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Achievement #1: Story related, we just grab it and let it iron our bleeding wounds.

As we go further just collect whatever you can find such as items and weapons too even killing enemies.


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Wild West
Fire the revolver
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Achievement #2: Found on the corpse after the area with 2 monsters and 1 save location, it is on the next area where you must go around the corpse. The bullet takes up 2 bar slots. Now fire it to the monster.



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Biohazard
Kill a mutated scientest
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Achievement #3: After you have a revolver, they do take 4 bullets to be killed.

Clear fewer levels until you reach the area of your first encounter with the lab rats.

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Squeakers
Kill a mutated lab rat
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Achievement #4: You first encounter the mutated rat after you press the green button. They are easy to kill but annoying to deal with.


There will be a total of 6 bags and each give +4 inventory slots, they are not hard to find but here it is in order:

Bag #1: We can find our first bag from here, just go through the laser scanner and grab it.



After going through levels, we reach to the next area which is where the shotgun is, go and figure around the area to unlock the room.

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Sawn Off
Fire the double barrel shotgun
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Achievement #5: As you progress through the game, it can be found from the level with 2 save points after you exit the hallway. After that, just like the revolver you use the shotgun against the monsters. The shell takes up 6 bar slots. Then fire anywhere as like always these achievements are very straightforward.



Bag #2: Laying next to the shotgun are 4 slots.


Straightforward, reach to the center area where you protect yourself against the hordes you've released via door.

Bag #3: In the middle with the button that released all the zombies.


Clear the hordes, we soon will go to the next level where we get our flare later.


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Requesting Evac
Fire a flare
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Achievement #6: Use the flare gun on the hordes. The flare ammo takes up 14 10 bar slots



Bag #4: Same room as the Flare Gun pickup.


After taking care of the level we will go to the next area.

1) Level: Maintenance, Crossbow, Reception
2) Bags: 6/6
3) Achievements: 13/24
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We reach to the area where there are pipes and of course new enemy.

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Sleeping Beauty
Kill a corpse trap
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Achievement #7: You can use 2 shells or 1 flare on them but I think I would not advise using the revolver since you need more than a bullet to kill them, just kill one Sleeping Beauty and pass the other one.


Bag #5: Top right of the room with the two caged Monkeys.


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Big Game Hunter
Kill a mutated lab monkey
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Achievement #8: When there are 2 corpses and 2 Monkeys locked inside the glass container, your flare gun is the best option, note that flare guns can ricochet when I hit the Sleeping Beauty aiming to the right and it hit back to the Monkey. Use 2 flares against them. There are also few of them as you progress but it's best if you do it where they won't attack you unless you get to the last one which is the biohazard area where there are so many crossbow bolts on the walls. You can also earn the Sleeping Beauty achievement here.




Alternatively, you can find the monkey one last time on the Biohazard room. Try to be careful otherwise your clapped for good.


https://psteamcommunity.yuanyoumao.com/sharedfiles/filedetails/?id=2880929863

Finally you reach to the cutscene but yeah just keep going.

An area where the monkey is on the loose, be careful where you make a sound, use the buttons to bait the monkey, after maybe trial and error on this move on.


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Medieval
Fire the crossbow
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Achievement #9: The crossbow can be found after you avoid the Monkey since they are too sensitive to sounds at the beginning of the level. Thankfully it does not use your slots but you can only carry 3 crossbow bolts in total unless you loaded one on your Crossbow as an extra.
It can kill the following enemies:
- Mutated scientist and rat in 1 shot.
- Sleeping Beauty in 2 shots.
- Mutated lab Monkey should take 3 shots also.
- Hunter are an exception but you can stagger the Hunter with it.
+ Silent enough to kill and you save your ammo too.



There is a boss room where the Monkey is, you might die here a lot but it's easy once you get the hang of it. You can get Big Game Hunter here by shooting two bolts and a fewer shots with your shotgun.

Another room has the monkey. You can use three bolt shots and the last monkey will die. Go to the next area.


A Hunter will be appearing later, you can for now stun the Hunter so keep it in mind. You can bait the Hunter to destroy the eggs so it can also kill the monsters.

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Predator
Stagger the teleporting hunter
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Achievement #10: You cannot kill the Hunter until his final fight initially but however you can temporarily stun him in less than 6 seconds. Wait for the Hunter to teleport and once he stops charging shoot it quick with the crossbow, an animation plays a little bit and then you will get the achievement after he teleports once again.

However, I think the Hunter can be stunned with other weapons like the shotgun for the best but like the Crossbow you have to wait for him to stop so you can shoot your guns since he might be at 12 hp in total so calculate according to your shots.



Hunter before being staggered by a crossbow



Bag #6: 2nd Level with the hunter. Bottom right of the 2nd bedroom of where you escape from the Hunter first encounter, you will come across the luxury rooms consisting of bedrooms. You will be greeted with a rat and three eggs but the bottom right corner is where you will get the last 4 slots bag for the achievement.


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Bag Master
Collect all inventory upgrades
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Achievement #11: If you've been following you'd get this achievement, otherwise load the save and go all the way from scratch where you last miss the bag.

Continue what you are doing until you reach the room where the final boss is, aka Exterminator.

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Exterminator
Kill the hunter for good
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Achievement #12: This is the final boss of this game, to take care of this a shotgun is a preferable option on each corners and watch out for those eggs the Hunter spawns. Thankfully you slide slightly faster and there are items such as the vaccine and ammo that the eggs spawns. Additionally, If you have flare ammo use them.

What you should be doing with what I mean is that you must use 2 shots of your shotgun against those eggs. The order is:
Top right > Bottom left > Bottom right > Top left





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Hardcore
Beat the game on hard mode
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Achievement #13: Congratulation on beating the story.

1) Level: Endemic
2) Achievements: 20/24
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Note:
I did this during beta and I tested by speedrunning this game from my other account during the Patch #3 Endemic mode, things were a lot easier with all upgrades and achievements easily earned one run for Endemic. As long as you know the mechanics easily trivial.

https://psteamproxy.yuanyoumao.com/news/app/2124780/view/6297768677843657574?l=english

Here we can run this Endemic Mode and collect upgrades until Floor 9. We must be wary of upgrades and enemy buffs, I provided another section for this mode so if you want to see what it looks like then do so.

• New Endemic mode aka roguelike Mode, I will chronologically put the achievements here as I progress.
  
• Kill one enemy, gain one money, buy upgrades with enough money and choose enemy buffs
  
• Bosses are spawned differently (example: Floor 3 will have Slashr or Blobr so when starting new playthrough you will fight a different boss).
  
• After buying upgrades you will keep it forever even before you start.
  
• You will have enough ammo no matter what, revolver is always your best friend.
  
• There is no enemy upgrade for Corpse Trap, only zombie scientists and Lab rats.
  
• I will not try to cover:
  - The whole map layout, they are randomised.
  - Enemy counts but I may put in what types you will encounter

https://youtu.be/v1hdIvrabNc

General Tips by Sayori:
- Avoid ever getting More Mass. Crossbow and flaming hand stop being a 1 hit kill.
- Hibernation kills count towards your money.
- Grab a crossbow and fast crank asap, it will carry you through almost everything besides bosses.
- Vampirism is extremely weak despite sounding good, go for Medical Satchel over it.
- Remember where you leave ammo and meds, especially on boss floors (3,6,9,12,etc), going back for stuff is what saved my runs.
- Use the revolver on eggs, it's ammo is plentiful and you aren't using up your crossbow shot incase it's an enemy


Enemies:

• Mutated Scientist
  
• Lab Rats

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Starting A Collection
Get 1 upgrade in Endemic Mode
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Achievement #14: Here you will find your first shop, three upgrades but to choose one. careful to where you waive your arms.


Enemies:

• Mutated Scientist
  
• Lab Rat

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Shopaholic
Get 5 upgrades in Endemic Mode
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Achievement #15: Self-explanatory.


Enemies:
Mutated Scientist
Lab Rat

Bosses:

• Ratr
  
• Slashr
  
• Misslr
  
• Blobs
  
• Spikr

Here is where the boss room is, for your advantage you can equip Fire Hand and hoard enough ammo and move them to the boss room which is what I did initially but after learning the boss phases I can be able to handle them easily. Depending which boss you got first I will list them all here but for each three levels they are sure to be one boss only.

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Ultimate Lab Rat
Kill the Ratr in Endemic Mode
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Achievement #16: This is an easy boss, at first annoying but even with or without upgrades (Thorny and burning hands for emergency) you can station yourself at the corner and after you hit the ratr he will retreat, watch out for the ! mark.

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Like A Soul
Kill the Slashr in Endemic Mode
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Achievement #17: This caught me by surprise, gonna be tricky to dodge but however try to dodge his upcoming slash attack and shoot him when he does his slash where you move away from so you can prepare to fire weapons such as the flare gun.

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Feature-Creep
Kill the Misslr in Endemic Mode
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Achievement #18: One also easy boss, wait for missiles to drop and then dodge, the boss will charge at you when the ! mark appears but he is way slow to respond. Missiles won't one-shot you. Fire hand works here.

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Anomalous Entities
Kill the Spikr in Endemic Mode
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Achievement #19: Move carefully to the center and shoot the white area with 2 shotgun shots assuming you got the upgrade which is possibly the pellet upgrade. The boss is extremely slow and has a sky blue line that I assume would harm you like the wall of spikes.

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Peak Invertebrate
Kill the Blobl in Endemic Mode
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Achievement #20: Blobr will immediately spin and fire lasers, this is of course easy to stay away from plus the lasers will deactivate and cooldown so you can pass through or reload. Next he will use a laser shield as I see it but you can dodge and shoot through it so wait for few seconds and then fire when his shield is gone even at the start.

1) Level: Endemic
2) Achievements: 24/24
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Enemies:

• Mutated Scientist
  
• Lab Rat
  
• Corpse Trap

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Novice Dungeoneer
Complete 3 floors in Endemic Mode
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Achievement #21: Self-explanatory.


Enemies:

• Mutated Scientist
  
• Lab Rat
  
• Corpse Trap

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Artificial Selection
Get 10 upgrades in Endemic Mode
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Achievement #22: You should get enough money to buy it.


Enemies:

• Mutated Scientist
  
• Lab Rat
  
• Corpse Trap
  
• Boss mentioned

Enemies:

• Mutated Scientist
  
• Lab Rat
  
• Eggs (ammo or enemies)

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Intermediate Dungeoneer
Complete 6 floors in Endemic Mode
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Achievement #23: Self-explanatory.[/td]

• Enemies:
  
• Mutated Scientist
  
• Lab Rat
  
• Eggs (ammo or enemies)

• Enemies:
  
• Mutated Scientist
  
• Lab Rat
  
• Eggs (ammo or enemies)
  
• Boss mentioned

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Expert Dungeoneer
Complete 9 floors in Endemic Mode
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Achievement #24: The last achievement.


After Floor 9, you can continue forward until you die but there is no point.

List of Upgrades:
I recommend buying all to keep them. There are few for starters such as Fire Hand, health and Pocket Hand, which I like to always set as my upgrade before starting.


Max upgrade will be shown as red numbered 3-4.


2023/05/26
https://psteamproxy.yuanyoumao.com/news/app/2124780/view/3691308397414330974?l=english

List of enemy upgrades:
Personally, I don't really recommend getting camouflage or the other one where SOME enemies flicker unless you get all the other upgrades or few guns but of course like I said revolver ammo with its upgrade is useful. Rats may be annoying so be patient. Lastly, Scientist zombies even with upgrades are easily dodgeable so no modifiers (unless you make them more buffed)

Endoparasitic is not perfect as well as the ending is not my cup of tea but it has a unique gameplay and I hope to see more games like this.



100% finished, keep it up people and good luck :)

If you want to consider donating, I have the link here so you can send your money. Otherwise if not then that is fine, continue using this guide at your own benefit I won't ask too much.
https://www.buymeacoffee.com/Diviision