Acid Gland (+50% Acid Resist, -15 Max HP) - Loot dropped by Humanpedes. Search them after one dies.




Calumet (+50% chance to dodge spirit attacks) - Complete all gold object quests for the Totem of Souls.



Dead Man's Hand (+15 Max HP, -25% Sneaking) - Across from the big hole in the wall in the upper floor of the Tower, on some rocks by a skeleton(presumably the former owner judging by the meat cleaver and rest of the skeleton bones nearby)






Ectoplasm (+20% chance for enemy ranged attack to miss) - Small burnt room, highest point in the church among other items.




Eyeballs (+5 range on ranged weapons) - Farmhouse at the Farm, in a box of body parts in front of the Fireplace.




Feather (+25% Stamina Regen/-10% Max Stamina(Says -25% but this is incorrect)) - Find one of these right after you get the axe at the start beside the candle straight ahead, or on almost any Birdman/North side of the Burial Grounds.




Glove (+15% faster reloading) - Unmarked camp, between Jim Hooper and the Tower on the map at the front of one of the tents.





Golden coin (Keeps you from getting a flaw from dying(MUST BE EQUIPPED)) - On top of the skeleton rack when you start a new game/Various enemies and areas.




Necklace with fangs (+50 Max Stamina, +25% Sneaking) - In the underground tunnel between the Fort and the Canyon, under the wooden walkway patrolled by two Birdmen, at the lowest area atop a crate.






Playing Card (+Loot chance) - Southern-most tower at the Fort, on a table with a couple bottles and a plate.





Mystical scalp (+30% Max HP/+25% bleed time/chance on self) - Burial Grounds, on one of two pair of pillars, one leaning against the other around the sacrificial circle where you find the Gold Ceremonial Dagger.





Shot Coin (+$3 per kill) - At the Tower, on the top floor by the candle on the ground.





Soul catcher (+50% Max Stamina) - Collapsed skeleton rack, east side of Burial Grounds/Sold by Jim Hooper.





Vendigo heart (-10% Max HP/Regen 1HP/8 secs) - On Vendigos after death, south part of the Burial Grounds on one of the skeleton racks.





Watch (Slows time by 15% for 1 second when you aim down sights, only every 5 seconds) - Sold by Jim Hooper.

Thanks to Skeezick and Sykomancer on Hyperstrange's discord server for hints on where to find the Dead Man's Hand!

I'll be adding screenshots of the map for each item tomorrow, as well as screenshotting the items in their natural spawn. If I missed any or you feel like this is incomplete or incorrect, please feel free to comment on this guide and I will update it as soon as possible. Thanks in advance!

2/18/22
Images added, edited some entries to add a more detailed explanation for where some of them are.