How to actually kill the Jaw Worm:
Ok so guys we all know the jaw worm is immune to all damage from cards, and starts with 100 artifact. The best build for jaw worm imo is silent. Generally the strat is to bring the card which makes every single one of your cards inflict 1 poison (i forgor what it called), upgrade it so it gains "innate" and then use it first thing. After this, your goal is simple:
Shiv Spamming.
Some other things that can help:
- Apotheosis/Upgraded Shiv Cards (for more shivs)
- Afterimage (sinergizes with shivs well and can help block damage earlier on)
- Wrath Stance (little known fact: wrath on silent makes all poison stacks apply twice (perfect for artifact))
I hope this small guide helped everyone!

I managed to get up an infinite combo of 30 dmg cards, and it took me about 10 minutes to work through them!!!

not final boss

Yes, great guide, I struggled against it for like 2k hours trying to pass the first floor, thanks! Now I can play the game!

maybe the answer is poison instead of running away

I tried this, but now I'm on Act 3 and there's three of them!! What do I do!?

Quality Guide, got stuck on jaw worm for 1600 out of my 1700 hours playing this game so im very glad to have found this

Sir,
you are technically correct. The best kind of correct.

good

low effort guide