LIGMA is part of the BOFA spectrum of conditions. LIGMA (Loose Internal Gene Mi-Asintits) is the second stage of BOFA (Biologically Offset Farkwnian Asintits). In this state, the disease interferes with the immune system and increases the risk of developing common infections such as tuberculosis.

Given the weakened immune system, many of the patients, such as popular Fortnite streamer Ninja, die on this stage of the Biologically Offset Farkwonian Asintits (BOFA). It is also the last treatable stage. Although not effective. there are treatments to LIGMA: LIGMA-BALLS (Bi-Asonurdick Lateral Lactatioustits Sequence) that, even though it's experimental, have shown some promise. With stopping the spread of BOFA at the LIGMA stages, it can stop patients from going into the third and final phase of the BOFA sequence: ETMA, (Entrenched Terminal Mi-Asintits)