In 2018, the Japanese national team finished 16th in the FIFA World Cup. As a result, the Japanese Football Union hires the soccer enigma Ego Jinpachi. His master plan to lead Japan to stardom is Blue Lock, a training regimen designed to create the world's greatest egotist striker. Those who fail Blue Lock will never again be permitted to represent Japan. Yoichi Isagi, an unknown high school student, decides to join the program in order to become the best player in the world.