Warhammer 40k: Where tactical nukes are used as anti-personnel landmines, personal weapons are fully automatic 20mm gyrojet grenade launchers, escort ships are capable of crippling planets by ramming them at full speed (I actually did the math one snowy day), billions die due to rounding errors in the Imperial Bureaucracy, where FTL involves jumping into hell, navigating by the beacon lit by souls, and jumping out before the daemons catch you...
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